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A novel combination therapy for treating vancomycin-resistant bacterial infections（图）
万古霉素 耐药细菌感染 联合疗法
2023/6/5
Researchers have developed a novel combination therapy using the anticancer agent mitoxantrone (MTX), together with an antibiotic, vancomycin, for treating bacteria that are resistant to the vancomyci...
Surprising beauty found in bacterial cultures（图）
Surprising beauty found bacterial cultures
2020/2/20
Microbial communities inhabit every ecosystem on Earth, from soil to rivers to the human gut. While single-species microbial cultures are often used in labs, in the real world, many different microbia...
Researchers find an alternative mode of bacterial quorum sensing（图）
Researchers alternative mode bacterial quorum sensing
2017/9/5
Whether growing in a puddle of dirty water or inside the human body, large groups of bacteria must coordinate their behavior to perform essential tasks that they would not be able to carry out individ...
By some estimates, bacterial strains resistant to antibiotics -– so-called superbugs – will cause more deaths than cancer by 2050.Colorado State University biomedical and chemistry researchers are usi...
Antibiotic breakthrough:Team discovers how to overcome gram-negative bacterial defenses
Antibiotic breakthrough gram-negative bacterial defenses
2017/7/20
Scientists report that they now know how to build a molecular Trojan horse that can penetrate gram-negative bacteria, solving a problem that for decades has stalled the development of effective new an...
PARTNERS IN PARASITISM,LICE AND THEIR BACTERIAL SIDEKICKS SHARE LONG HISTORY
PARTNERS IN PARASITISM LICE AND THEIR BACTERIAL SIDEKICKS SHARE LONG HISTORY
2017/4/27
A Florida Museum of Natural History study provides new insights into the complex, shared history between blood-sucking lice and the vitamin-producing bacterial sidekicks that enable them to parasitize...
Genomics Technique Could Accelerate Detection of Foodborne Bacterial Outbreaks
Genomics Technique Accelerate Detection Foodborne Bacterial
2016/12/13
A new testing methodology based on metagenomics could accelerate the diagnosis of foodborne bacterial outbreaks, allowing public health officials to identify the microbial culprits in less than a day....
Scientists model outer membrane of 12 bacterial species to speed new drugs for 'bad bugs'
Scientists model membrane 12 bacterial species speed new drugs bad bugs
2016/11/4
As bacteria change their behavior to foil the drugs designed to kill them, illnesses that were once relatively easy to treat become difficult to cure. The phenomenon is known as antibiotic resistance,...
We generally think of inheritance as the genetic transfer from parent to offspring and that evolution moves toward greater complexity. But there are other ways that genes are transferred between organ...
Revving the microbial engine:Horsepower versus fuel efficiency in bacterial genomes
Revving the microbial engine Horsepower fuel efficiency bacterial genomes
2016/9/29
Microbes that can reproduce rapidly in times of plenty have an evolutionary stockpile of extra genes that allows them to quickly respond to changing conditions such as oil spills or outbreaks of intes...
Energetics of Primary Charge Separation in Bacterial Photosynthetic Reaction Center Mutants:Triplet Decay in Large Magnetic Fields
horseradish peroxidase lignin peroxidase enzymatic oxidations N-demethylation methylene blue azure B azure C
2016/5/24
The triplet state of aromatic molecules forms and decays by intersystem crossing, as originally demonstrated by Kasha and Lewis. By contrast, the triplet state of the primary electron donor, 3 P, in p...
The Mechanism of Triplet Energy Transfer from the Special Pair to the Carotenoid in Bacterial Reaction Centers
Triplet Energy Transfer Carotenoid Bacterial Reaction Centers
2016/5/23
The kinetics of triplet energy transfer from the primary electron donor P, a bacteriochlorophyll dimer, to the carotenoid were measured in the M182HL mutant of Rhodobacter sphaeroides photosynthetic r...
Temperature Dependece of the Qy Resonance Raman Spectra of Bacteriochlorophylls,the Primary Electron Donor,and Bacteriopheophytins in the Bacterial Photosynthetic Reaction Center
Bacteriochlorophylls chemistry Electron Transport Infrared Rays Light-Harvesting Protein Complexes Pheophytins chemistry Photosynthetic Reaction Center Complex Proteins chemistry Research Support, U.S. Gov't, Non-P.H.S. Research Support,U.S. Gov't,P.H.S. Rhodobacter sphaeroides chemistry Spectrophotometry
2016/5/23
Qy-excited resonance Raman spectra of the accessory bacteriochlorophylls (B), the bacteriopheophytins (H), and the primary electron donor (P) in the bacterial photosynthetic reaction center (RC) of Rh...
Rapid Isolation of Bacterial Photosynthetic Reaction Centers with an Engineered Poly-Histidine Tag
photosynthetic reaction center poly-histidine tag isolation method (bacterium)
2016/5/23
A very rapid method for isolating bacterial photosynthetic reaction centers (RCs) of high purity and yield is described. A poly-histidine tag is engineered at the C-terminus of the RC M-subunit, allow...
Mg Coordination by Amino Acid Side Chains is Not Required for Assembly and Function of the Special Pair in Bacterial Photosynthetic Reaction Centers
Amino Acids Fourier Analysis Light-Harvesting Protein Complexes Magnesium xidation-Reduction Photosynthetic Reaction Center Complex Proteins Spectrometry,Fluorescence Spectrum Analysis, Raman
2016/5/23
A conserved histidine serves as the axial ligand to the Mg of bacteriochlorophylls in the photosynthetic reaction center (RC) and many other photosynthetic systems. The histidine axial ligands to each...