搜索结果: 1-15 共查到“生物学 Mutation”相关记录27条 . 查询时间(0.062 秒)
Genetic mutation trade-offs lead to parallel evolution
Genetic mutation trade-offs parallel evolution
2017/7/20
Organisms in nature adapt and evolve in complex environments. For example, when subjected to changes in nutrients, antibiotics, and predation, microbes in the wild face the challenge of adapting multi...
Identification and characterization of the yls mutation in rice (Oryza sativa L.) with lower photosynthetic pigment content
chloroplast development map-based cloning SRP54 protein yellow-green leaf mutant
2016/12/8
Normal chloroplast development in rice is essential for photosynthesis and yield potential. To explore the physiological and molecular mechanism of chloroplast development, we isolated the rice mutant...
Surface mutation lets canine parvovirus jump to other species
Surface mutation canine parvovirus jumpother species
2016/4/25
Canine parvovirus, or CPV, emerged as a deadly threat to dogs in the late 1970s, most likely the result of the direct transfer of feline panleukopenia or a similar virus from domesticated cats.CPV has...
Crocodilians, including the Australian saltwater crocodile, mutate at about a quarter of the rate of birds, new research has revealed.The discovery is the result of genome sequencing three crocodilian...
Characterization of {\it midline uncoordinated\/}, a mutation affecting behavior and neuroanatomy in Drosophila
Genetics gene gene elements neurons
2014/12/11
Genetic screens which assay behavior have been successfully used to identify genes required for neural function. This thesis is the analysis of midline uncoordinated (muc), a mutation identified for i...
Cloning and functional characterization of the zebrafish mutation belladonna
Belladonna zebrafish mutations mutagenic screen and identify genes the retina the nerve cross the pupil
2014/12/11
The zebrafish belladonna (bel) mutation was identified in a large-scale mutagenesis screen to identify genes involved in retino-tectal pathfinding in Tubingen, Germany. In bel mutants, after exiting t...
A University of Texas at Arlington team exploring pigeons as a model for vertebrate evolution has uncovered that mutations and interactions among just three genes create a wide range of color variatio...
University of Texas (UT) at Arlington researchers, working in parallel with researchers at the University of Utah, examined three genes that control multiple color phenotypes, or appearances, in pige...
Genotype and Allelic Frequencies of a Newly Identified Mutation Causing Blindness in Jordanian Awassi Sheep Flocks
Awassi Sheep, Day Blindness, CNGA3 Gene, PCR- RFLP
2016/5/9
A total of 423 blood samples were collected (during 2009 and 2010) from all the ram holdings at three major Jordanian governmental Awassi breeding stations (Al-Khanasry, Al-Mushairfa and Al-Fjaje) and...
On the Impact of Mutation-Selection Balance on the Runtime of Evolutionary Algorithms
Mutation-Selection Evolutionary Algorithms
2011/1/6
The interplay between mutation and selection plays a fundamental role in the behaviour of evolutionary algorithms (EAs). However, this interplay is still not completely understood. This paper presents...
The statistical mechanics of a polygenic characterunder stabilizing selection, mutation and drift
statistical mechanics polygenic characterunder stabilizing selection mutation drift
2010/11/15
By exploiting an analogy between population genetics and statistical mechanics, we study the evolution of a polygenic trait under stabilizing selection, mutation, and genetic drift. This requires us ...
ENU诱导带LacZ靶基因的λgt11 DNA突变分子机理的初步研究①Mutation Study of λgt11 DNA with LacZ Induced by ENU
LacZ基因 突变 体外重包装 诱变剂 DNA测序
2008/1/21
摘要采用ENU(乙基亚硝基脲)作用于裸露的 λgt11 DNA，经体外重包装，转染宿主菌 E. coli Y1090，在含底物X-gal，诱导剂IPTG的选择性培养基上铺皿，发现被处理的 λgt11 DNA除了使噬菌体存活率下降外，还出现了靶基因“LacZ”较高频率的突变。其中以二甲基亚砜(DMSO)为溶剂，当存活率分别为3.5×10-3、1.6×10-3和5.5×10-4 时，相应的突变率依次为...
中国人扩张型心肌病与受磷蛋白基因关系的研究 Association between Mutation of Phospholamban Gene and Dilated Cardiomyopathy
扩张型心肌病 受磷蛋白基因 突变
2008/1/8
摘要
受磷蛋白（phospholamban）是心肌收缩的一个重要调节因子，可抑制心肌肌浆网钙ATPase的活性、降低其对钙的亲和力。正常情况下，受磷蛋白可被不同的蛋白激酶磷酸化从而解除其肌浆网钙ATPase的抑制作用。国外两个DCM家系研究发现受磷蛋白基因突变与DCM的发生有关，研究目的旨在探讨中国人群心肌特异性受磷蛋白基因突变与特发性扩张型心肌病发病的关系。收集60例确诊的特发性扩张型心肌病...
人类单纯性先天性心脏病中TBX5基因的突变及表达研究 Studies on the Mutation and Expression of TBX5 Gene in Human Simple Congenital Heart Disease
TBX5基因 心脏发育 突变 表达
2007/12/31
摘要应用PCR-DGGE方法在61个单纯性先天性心脏病核心家系共216位成员中检测TBX5基因8个外显子的突变情况；以β-actin作为内对照对单纯性先天性心脏病患者（房间隔缺损12例、室间隔缺损16例、法洛四联症6例）和3个非先天性心脏病患者（正常对照）心肌标本进行RT-PCR扩增和定量分析，观察TBX5基因在mRNA水平有无差异。研究了人类单纯性先天性心脏病患者中TBX5基因突变及表达情况。在...
大肠杆菌FC40系统静止期突变中的F因子转移The Occurrence of Actual F Factor Transfer during the Stationary-phase Mutation in Escherichia coli FC40
大肠杆菌FC40系统 适应性突变 F因子转移
2007/12/31
摘要本研究采用大肠杆菌GM133 rifr细胞和营养收集细胞HB214 strr进行适应性突变实验。在混合30min和2d 后添加链霉素杀死GM133基因型细胞，继续培养5d后，在选择平板上出现了一定数量的lac+strr基因型回复突变菌落。根据这些突变菌落的数量，估计在lac+突变产生之前，GM133和HB214细胞之间的接合频率分别为0.07%和7.47%。在培养了7d的选择平板上添加含链霉素...