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中国科学院上海营养与健康研究所王莹、时玉舫研究组合作发现p53通过调控OPG影响间充质干细胞成骨分化以及肿瘤相关骨骼重塑的新机制（图）
王莹 时玉舫 p53 OPG 间充质 干细胞 成骨分化 肿瘤 骨骼重塑 新机制
2020/7/24
2020年7月22日，国际著名学术期刊Cell Death & Differentiation在线发表了中国科学院上海营养与健康研究所王莹、时玉舫课题组题为“Loss of p53 in mesenchymal stem cells promotes alteration of bone remodeling through negative regulation of osteoproteger...
Estrogen and progesterone regulate p53 activity in the mouse mammary epithelium through transforming growth factor beta dependent pathways
P53 protein and tumor formation mammary gland p53 fertility estrogen and progesterone p53 radiation cells DNA damage
2014/12/11
Proper regulation of the p53 protein plays a critical role in suppressing tumor formation in a variety of tissues including the mammary gland. Activity of the p53 pathway is diminished in the mammary ...