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Four-vessel occlusion model,Both vertebral arteries are cauterized,Both common carotid arteries are clamped,Duration of ischemia: 15–30 min.
Induction of Tolerance to Focal Ischemia in Rat Brain: Dissociation Between Cortical Lesioning and Spreading Depression
Rat Brain Cortical Lesioning Spreading Depression
2014/3/31
Cortical application of KCl has previously been
shown to induce tolerance to a subsequent episode of cerebral
ischemia. KCl triggers recurrent episodes of cortical spreading
depression and produces...