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Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful p...
Genetic engineering and personalized cell therapies could transform health care. In recent years, stem cells and gene-editing tools like CRISPR have been making headlines for the possibilities they of...
Scientists discover a new way of sharing genetic information in a common ocean microbe（图）
海洋微生物 共享 遗传信息 原绿球菌 光合生物 基因转移
2023/6/21
From the tropics to the poles, from the sea surface to hundreds of feet below, the world’s oceans are teeming with one of the tiniest of organisms: a type of bacteria called Prochlorococcus, which des...
New CRISPR-based tool inserts large DNA sequences at desired sites in cells（图）
CRISPR 新型工具 大DNA序列 PAST 基因工程
2023/6/21
Building on the CRISPR gene-editing system, MIT researchers have designed a new tool that can snip out faulty genes and replace them with new ones, in a safer and more efficient way.
In recent years, scientists who study gene expression in cells have used a method that essentially pins a tail on RNA and tracks their whereabouts. However, certain types of RNA evade the process. Now...
The Human Genome Project was an ambitious initiative to sequence every piece of human DNA. The project drew together collaborators from research institutions around the world, including MIT's Whitehea...
When Sharif Tabebordbar was a teenager, his father began having trouble walking. Soon, he became wheelchair-bound and was diagnosed with a rare genetic muscle disease.
New gene-editing technique shows promise against sickle cell disease（图）
镰状细胞性贫血 基因编辑技术 一次性治疗
2023/6/21
Ateam of researchers led by scientists from Harvard and the Broad Institute used a new gene-editing technique to successfully treat sickle cell disease in mice. This advancement could one day lead to ...
Gene editing, or purposefully changing a gene’s DNA sequence, is a powerful tool for studying how mutations cause disease, and for making changes in an individual’s DNA for therapeutic purposes. A nov...
Genetic testing has a data problem. New software can help（图）
Genetic testing；data problem New software
2019/10/30
In recent years, the market for direct-to-consumer genetic testing has exploded. The number of people who used at-home DNA tests more than doubled in 2017, most of them in the U.S. Some 1 in 25 Americ...
Why might the finding of a new genetic association with inflammatory bowel disease be of potential value in disease control?
new genetic association inflammatory bowel disease potential value disease control
2018/11/20
Inflammatory bowel disease (IBD) has long been recognized as an exaggerated inflammatory response to common antigenic stimuli in the gut. Ulcerative colitis (UC) (1) and Crohn disease (CD) (2) are the...
Genomics Discovery Paves Way For Possible New Treatments Of Genetic Disorders,Diseases
Genomics Paves Way New Treatments Genetic Disorders Diseases
2017/10/24
NSF-funded researchers studying how a bacterium's immune system fights off viruses uncovered a powerful new gene-editing technique called CRISPR-Cas9.CRISPR-Cas9 acts like a pair of molecular-sized sc...
Why it’s difficult to predict evolutionary fate of a new trait（图）
evolutionary fate new trait
2017/9/20
The phrase “survival of the fittest” makes the principle of evolution by natural selection easy to understand — individuals with a trait that adapts them well to their circumstances are more likely to...
New genomic insights reveal a surprising two-way journey for apple on the Silk Road（图）
New genomic two-way journey apple the Silk Road
2017/9/5
Centuries ago, the ancient networks of the Silk Road facilitated a political and economic openness between the nations of Eurasia. But this network also opened pathways for genetic exchange that shape...
NSF EPSCoR awards new projects to help understand connections between genes and organisms' characteristics（图）
NSF EPSCoR new projects connections between genes and organisms' characteristics
2017/9/4
The National Science Foundation (NSF) has made eight awards totaling $41.7 million for projects aimed at building capacity to research a national priority area: understanding the relationship in organ...